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The Bio2RDF project aims to transforms silos of life science data into a globally distributed network of linked data for biological knowledge discovery. Bio2RDF creates and provides machine understandable descriptions of biological entities using the RDF/RDFS/OWL Semantic Web languages. Using both syntactic and semantic data integration techniques, Bio2RDF seamlessly integrates diverse biological data and enables powerful new SPARQL-based services across its globally distributed knowledge bases.