Postfix is an attempt to provide an alternative to the widely-used Sendmail program. Postfix attempts to be fast, easy to administer, and hopefully secure, while at the same time being sendmail compatible enough to not upset your users.
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The Postfix Milter client would be out of step with a Milter application after the application sent a "quarantine" request at end-of-message time. The Milter application would still be in the end-of-message state, while Postfix would already be working on the next SMTP event, typically QUIT or MAIL FROM. In the latter case, Milter responses for the previously-received email message would be applied towards the next MAIL FROM transaction. The Postfix SMTP server would abort with an "unexpected lookup table" error when an SMTPD policy server was mis-configured in a particular way.